SNAKE VENOM

Key Features

1. Polyclonal Antibody Formulation
   • Derived from immunized animals (usually horses or sheep).
   • Targets multiple venom components from different snake species.
2. Species-Specific or Polyvalent
   • Monovalent: Effective against a single snake species.
   • Polyvalent: Neutralizes venom from multiple medically important snake species (common in India, Africa, Southeast Asia).
3. Lyophilized or Liquid Form
   • Lyophilized (freeze-dried): Longer shelf-life, requires reconstitution.
   • Liquid: Ready to use, but shorter shelf-life.
4. Rapid Onset of Action
   • Neutralizes venom toxins quickly after IV administration, reducing systemic effects like neurotoxicity, coagulopathy, and tissue necrosis.
5. Standardized Potency
   • Potency tested and standardized using venom challenge tests.
   • Doses expressed in “antivenom units” to match venom toxicity.
6. Sterile & Pyrogen-Free
   • Manufactured under strict GMP (Good Manufacturing Practices).
   • Safe for intravenous administration.
7. Minimal Protein Load
   • Highly purified to reduce allergic reactions or serum sickness.
   • Some modern ASVs are enzyme-refined (Fab or F(ab’)2 fragments).
8. WHO Prequalification or Local Regulatory Approval
   • Ensures safety, efficacy, and quality.